Hormozgan Medical Journal

Published by: Kowsar

Evaluation of the Effect of Vitamin D on the Length of Hospital Stay in Children with Gastroenteritis Aged 3 Months to 14 Years Admitted to the Pediatric Hospital of Bandar Abbas

Mohammad Bagher Rahmati 1 , * , Alireza Nikbakht 2 and Mehran Ahmadi 1
Authors Information
1 Department of Pediatric Infectious Diseases, Children’s Clinical Research Development Center, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
2 Student Research Committee, Department of Pediatrics, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Article information
  • Hormozgan Medical Journal: September 30, 2018, 22 (3); e86323
  • Published Online: November 21, 2018
  • Article Type: Research Article
  • Received: November 12, 2018
  • Accepted: November 14, 2018
  • DOI: 10.5812/hmj.86323

To Cite: Rahmati M B , Nikbakht A , Ahmadi M . Evaluation of the Effect of Vitamin D on the Length of Hospital Stay in Children with Gastroenteritis Aged 3 Months to 14 Years Admitted to the Pediatric Hospital of Bandar Abbas, Hormozgan Med J. 2018 ; 22(3):e86323. doi: 10.5812/hmj.86323.

Copyright © 2018, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Bener A, Al-Ali M, Hoffmann GF. Vitamin D deficiency in healthy children in a sunny country: Associated factors. Int J Food Sci Nutr. 2009;60(Supp 5):60-70. doi: 10.1080/09637480802400487. [PubMed: 18946796].
  • 2. Walker CLF, Rudan I, Liu L, Nair H, Theodoratou E, Bhutta ZA, et al. Global burden of childhood pneumonia and diarrhoea. Lancet. 2013;381(9875):1405-16. doi: 10.1016/S0140-6736(13)60222-6. [PubMed: 23582727].
  • 3. Pickering LK, DuPont HL, Olarte J, Conklin R, Ericsson C. Fecal leukocytes in enteric infections. Am J Clin Pathol. 1977;68(5):562-5. [PubMed: 920652].
  • 4. Liu L, Oza S, Hogan D, Chu Y, Perin J, Zhu J, et al. Global, regional, and national causes of under-5 mortality in 2000-15: An updated systematic analysis with implications for the sustainable development goals. Lancet. 2016;388(10063):3027-35. doi: 10.1016/s0140-6736(16)31593-8.
  • 5. Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, et al. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): A prospective, case-control study. Lancet. 2013;382(9888):209-22. doi: 10.1016/S0140-6736(13)60844-2. [PubMed: 23680352].
  • 6. Mascarenhas JD, Lima CS, de Oliveira DS, Guerra Sde F, Maestri RP, Gabbay YB, et al. Identification of two sublineages of genotype G2 rotavirus among diarrheic children in Parauapebas, Southern Para State, Brazil. J Med Virol. 2010;82(4):712-9. doi: 10.1002/jmv.21735. [PubMed: 20166186].
  • 7. Holick MF. Vitamin D: Extraskeletal health. Rheum Dis Clin North Am. 2012;38(1):141-60. doi: 10.1016/j.rdc.2012.03.013. [PubMed: 22525849].
  • 8. Norris JM. Can the sunshine vitamin shed light on type 1 diabetes? Lancet. 2001;358(9292):1476-8. doi: 10.1016/S0140-6736(01)06570-9. [PubMed: 11705556].
  • 9. Chen S, Sims GP, Chen XX, Gu YY, Chen S, Lipsky PE. Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation. J Immunol. 2007;179(3):1634-47. [PubMed: 17641030].
  • 10. Thornton KA, Marin C, Mora-Plazas M, Villamor E. Vitamin D deficiency associated with increased incidence of gastrointestinal and ear infections in school-age children. Pediatr Infect Dis J. 2013;32(6):585-93. doi: 10.1097/INF.0b013e3182868989. [PubMed: 23340562].
  • 11. Pike JW, Meyer MB. Fundamentals of vitamin D hormone-regulated gene expression. J Steroid Biochem Mol Biol. 2014;144 Pt A:5-11. doi: 10.1016/j.jsbmb.2013.11.004. [PubMed: 24239506]. [PubMed Central: PMC4144817].
  • 12. Veldman CM, Cantorna MT, DeLuca HF. Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system. Arch Biochem Biophys. 2000;374(2):334-8. doi: 10.1006/abbi.1999.1605. [PubMed: 10666315].
  • 13. Rigby WF, Stacy T, Fanger MW. Inhibition of T lymphocyte mitogenesis by 1,25-dihydroxyvitamin D3 (calcitriol). J Clin Invest. 1984;74(4):1451-5. doi: 10.1172/JCI111557. [PubMed: 6332829]. [PubMed Central: PMC425314].
  • 14. Provvedini DM, Tsoukas CD, Deftos LJ, Manolagas SC. 1,25-dihydroxyvitamin D3 receptors in human leukocytes. Science. 1983;221(4616):1181-3. [PubMed: 6310748].
  • 15. Somnath SH, Biswal N, Chandrasekaran V, Jagadisan B, Bobby Z. Therapeutic effect of vitamin D in acute lower respiratory infection: A randomized controlled trial. Clin Nutritr ESPEN. 2017;20:24-8. doi: 10.1016/j.clnesp.2017.02.003. [PubMed: 29072165].
  • 16. Amrein K, Schnedl C, Holl A, Riedl R, Christopher KB, Pachler C, et al. Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: The VITdAL-ICU randomized clinical trial. JAMA. 2014;312(15):1520-30. doi: 10.1001/jama.2014.13204. [PubMed: 25268295].
  • 17. Langlois PL, Szwec C, D'Aragon F, Heyland DK, Manzanares W. Vitamin D supplementation in the critically ill: A systematic review and meta-analysis. Clin Nutr. 2018;37(4):1238-46. doi: 10.1016/j.clnu.2017.05.006. [PubMed: 28549527].
  • 18. Sankar J, Lotha W, Ismail J, Anubhuti C, Meena RS, Sankar MJ. Vitamin D deficiency and length of pediatric intensive care unit stay: A prospective observational study. Ann Intensive Care. 2016;6(1):3. doi: 10.1186/s13613-015-0102-8. [PubMed: 26745966]. [PubMed Central: PMC4706541].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments