Distribution and antibiogram pattern of Acinetobacter infections in Shahid Mohammadi Hospital , Bandar Abbas, Iran

AUTHORS

Pyrooz Poorzargar 1 , Sedigheh Javadpour 2 , * , Afsaneh Karmostaji 3

1 Infectious and Tropical Diseases Research Center , Hormozgan Universit y of Medical Sciences, Bandar Abbas, Iran.

2 deprtment of Microbiology , Infectious and Tropical Diseases Research Center, Hormozgan Health Istitute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

3 eprtment of Microbiology , Infectious and Tropical Diseases Research Center, Hormozgan Health Istitute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

How to Cite: Poorzargar P , Javadpour S, Karmostaji A. Distribution and antibiogram pattern of Acinetobacter infections in Shahid Mohammadi Hospital , Bandar Abbas, Iran, Hormozgan Med J. 2017 ; 20(6):e87374. doi: 10.18869/acadpub.hmj.20.6.422.

ARTICLE INFORMATION

Hormozgan Medical Journal: 20 (6); e87374
Published Online: March 06, 2017
Article Type: Research Article
Received: January 15, 2016
Accepted: March 06, 2017
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Abstract

Introduction: Acinetobacter species are important opportunistic pathogens, widely spread in hospitals' environment and responsible for different health care associated infections. Because of its ability to rapidly develop resistance to the major groups of antibiotics, treatment of Acinetobacter infections is difficult and antibiotic susceptibility tests can help in choosing the best antibiotics, decreasing the cost and duration of hospitalization. The goals of this study were to determine frequency and antimicrobial susceptibility pattern of Acinetobacter species, clinical parameters and outcomes of patients, in Shahid Mohammadi hospital, Bandar Abbas.

Methods: Between April 2010 and March 2011, a total of 2132 positive cultures were obtained from various clinical specimens of hospitalized patients. Suspicious isolates of Acinetobacter were identified by routine microbiological methods. Antibiogram patterns of isolates for 12 currently used antibiotics were determined by Kirby-Bauer method. Clinical and microbiological data of patients was analyzed by SPSS 16 software.

Results: A total of 68 (3.2%) Acinetobacter species was isolated. Acinetobacter isolates was mostly obtained from ICU (24 cases, 35.8%) and emergency (12 cases, 17.9%) wards, and trachea was the major site of infection (41.2%). Colistin with 83.7% susceptibility rate was the most effective antibiotic, followed by ofloxacine 47.4% and chloramphenicol 39.5%. A high rate of resistance was observed to meropenem (98.1%), and cefepime (90.4%). Mortality rate was 14.7% in patients, mostly because of bacteremia.

Conclusion: Because of its serious infections and high-drug resistance, continuous monitoring of antimicrobial susceptibility and strict adherence to infection guidelines are essential to prevent and decrease Acinetobacter infections.

Keywords

Acinetobacter Microbiasensitivity Test Intensive Care Units

© 2017, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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