Frequency of Vancomycin-Resistant Enterococci Isolated from Clinical Samples of Shahid Mohammadi Hospital through the E-Test Method

AUTHORS

Zeynab Ghalandarzadeh Daryaii 1 , Sedigheh Javadpour 2 , * , Mohammad Kargar 3

1 MSc Student of Microbiology, Infectious Disease Research Center, Hormozgan University of Medical Sciences, Banadr Abbas, Iran.

2 Associate Professor Department of Microbiology, Molecular Medicine Research Center, Hormozgan University of Medical Sciences, Banadr Abbas, Iran.

3 Associate Professor Department of Microbiology, Islamic Azad University, Jahrom Branch, Jahrom, Iran.

How to Cite: Ghalandarzadeh Daryaii Z, Javadpour S, Kargar M . Frequency of Vancomycin-Resistant Enterococci Isolated from Clinical Samples of Shahid Mohammadi Hospital through the E-Test Method, Hormozgan Med J. 2015 ; 19(4):e87553.

ARTICLE INFORMATION

Hormozgan Medical Journal: 19 (4); e87553
Published Online: November 20, 2013
Article Type: Research Article
Received: July 20, 2013
Accepted: November 20, 2013

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Abstract

Introduction: Enterococci are gram-positive coccoid bacteria that are present in the
normal flora of the gastrointestinal tract in human, and many mammals and birds, as well as
the environment. Vancomycin-resistant Enterococci (VRE) are a major and rising problem
in hospitals throughout the world. The present study aimed to investigate the frequency of
strains of Enterococci and the pattern of drug sensitivity in clinical samples.
Methods: This cross-sectional study was conducted on 54 samples of Enterococcus in
2012. The diagnostic kit of RapID STR System was used for identification of Enterococcus
species. Antibiotic sensitivity was determined by Kirby-Bauer disk diffusion method
according to CLSI instructions. E-Test was used to determine Vancomycin MIC.
Results: Of the 54 isolates of Enterococci, the obtained strains included 38 E. faecalis
(70.40%), 10 E. faecium (18.50%), 3 E. hirae (5.55%), one E. mudtii (1.85%), one E.
durans (1.85%), and one E. avium (1.85%). Thirteen strains had vancomycin MIC>32
μg/mL. They had the highest resistance to gentamicin and cephalexin by 70.40% and the
lowest resistance to linezolid by 3.70%. The highest resistant strain was obtained from urine
(76.9%) and internal ward (46.1%).
Conclusion: The substantial abundance of VRE isolated from the study area necessitates
the performance of controlling measures.

Keywords

Vancomycin-Resistant Enterococcus - Antibiotic – Hospital

© 2015, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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