Changes in Omentin-1 and Some Metabolic Parameters Following a Period of Aerobic Exercise in Middle-Aged Men


Kamran Rafieemoghaddam 1 , Ahmad Mohammadi Moghaddam 2 , * , Saeed Amiriyan 3 , Naser Behpoor 4


1 MSc of Exercise Physiology, Islamic Azad University, Borujerd Branch, Borujerd.

2 MSc of Physical Education and Sports Science, Islamic Azad Univerity, Khorramabad Branch, Khorramabad.

3 MSc of Physical Education and Sports Science, Islamic Azad University, Borujerd Branch, Borujerd.

4 Assistant Professor Department of Exercise Physiology, Razi University of Kermanshah, Kermanshah, Iran.


Hormozgan Medical Journal: 19 (4); e87567
Published Online: September 10, 2014
Article Type: Research Article
Received: May 05, 2014
Accepted: September 10, 2014




Introduction: Studies have reported hyperlipidemia and its complications, such as
diabetes, along with aging. Omentin-1, on the other hand, is a protein that is secreted in
visceral adipose tissue and can increase insulin sensitivity. This study aimed at evaluating
the effect of aerobic exercise on resting levels of omentin-1, C-reactive protein, and some
metabolic parameters in middle-aged men.
Methods: A total of 30 volunteers were enrolled in the study. The subjects were randomly
divided into two groups and their blood samples were collected. Those in the experimental
group participated in an eight-week aerobic program of running with 35-40% of maximum
heart rate for 10 minutes in the first week which augmented to 70% of maximum heart rate
for 30 minutes in the eighth week. Blood samples were collected again from both groups
(post-test) 48 hours after the eight weeks.
Results: The results showed that aerobic exercise for eight weeks led to a significant
increase in resting levels of omentin-1 and high density lipoprotein (pvalue=0.001 and
pvalue=0.001, respectively). The exercise resulted also in a significant decrease in resting
levels of C-reactive protein and low-density lipoprotein (pvalue=0.001 and pvalue=0.003,
respectively), and non-significant decrease in total cholesterol in middle-aged men
Conclusion: According to the results of this study, middle-aged men can prevent
complications arising from decreased omentin-1 and HDL and increased levels of CRP,
LDL, and TC by enjoying from aerobic exercise.


Omentin - Lipoprotein – Middle Age

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