Interactive effect of exercise training with ω-3 supplementation on resting levels of TNF-α and IL-10 in Karat Men

AUTHORS

Parvin Farzanegi 1 , * , Mahla Mohammad Zadeh 2 , Mohammad Ali Azarbayjani 3

1 Assistant Professor Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran.

2 MSc of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran.

3 Professor Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.

How to Cite: Farzanegi P , Mohammad Zadeh M, Azarbayjani M A . Interactive effect of exercise training with ω-3 supplementation on resting levels of TNF-α and IL-10 in Karat Men, Hormozgan Med J. 2014 ; 18(1):e87842.

ARTICLE INFORMATION

Hormozgan Medical Journal: 18 (1); e87842
Published Online: February 06, 2013
Article Type: Research Article
Received: July 27, 2012
Accepted: February 06, 2013

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Abstract

Introduction: Perform heavy exercise training, causing a variety of changes including a reduction in performance. Few human studies have been examined of supplemental ω-3 and exercise, then the aim of this study was to study the interactive effect of exercise and ω-3 on resting levels of TNF-α and IL-10 in elite Karate and compared with untrained.
Methods: In this quasi-experimental study 42 healthy young male elite karate and non-athletes, were randomly divided into study groups. Athletes: 1- ω -3 and exercise, 2- placebo and exercise,3- exercise and non-athletes: 1- ω -3, 2- placebo,3- control. Athletes groups performed pre-season practice in 65% to 80% VO2 max. Consumption of ω -3 was 1800mg/day for 4 weeks. Blood sampling done 48 hours before, 12 hours fasting after protocol. TNF-α and IL-10 were measured by ELISA and LDL, HDL Enzymatic methods. Results: Exercise training with ω-3 for 4 weeks do not have a significant effect on resting levels of IL-10، TNF- α ،HDL و LDL (P>0.05). Then ω-3 do not have a significant effect in non-athletes (P>0.05).
Conclusion: The results showed that Although the consumption of ω-3 do not have significant changes in TNF-α and IL-10, but can slightly reduced TNF-α and increase in the IL-10, that confirm its positive effects on inflammatory factors. However, more research seems necessary in this context.

Keywords

IL_10 - TNFα- Exercise

© 2014, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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