Predictive value of umbilical cord serum bilirubin for subsequent jaundice in healthy term newborns

AUTHORS

Salma Naderi 1 , * , Shahram Zare 2 , Mahshid Ahmadi 3 , Shahrokh Rajaei 4 , Shahrouz Maasoum 5

AUTHORS INFORMATION

1 Assistant Professor Department of Pediatrics, Clinical Research Development Center of Children Hospital,

2 Associate Professor Department of Community Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

3 Assistant Professor Department of Pediatrics, Clinical Research Development Center of Children Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

4 Associate Professor department of Pediatrics, Children Clinical Research Center development Unit, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

5 Pediatrician, Boshehr University of Medical Sciences, Boshehr, Iran.

ARTICLE INFORMATION

Hormozgan Medical Journal: 17 (1); e87918
Published Online: September 25, 2012
Article Type: Research Article
Received: July 22, 2012
Accepted: September 25, 2012

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Abstract

Introduction: Jaundice is common in neonatal period and in severe type cause
neurotoxicity (Kernicterus), so diagnosis and treatment of severe hyperbilirubinemia is very
important. This study investigates the predictive value of umbilical cord serum bilirubin
(UCSB) for subsequent jaundice in healthy term newborns.
Methods: In this cross-sectional study, 341 normal term (gestational age>37 week) and near
term (gestational age=35-37 week) from Bandar Abbas Shariati hospital with birth weight
above 2500gr were selected randomly. Asphyxia and congenital anomalies cases and those
who need resuscitation were excluded from the study. All neonates according to the umbilical
cord blood bilirubin level were divided in two groups: UCSB≥2 mg/dl and UCSB<2 mg/dl.
Then, in 3rd day after birth, all neonates according to total serum bilirubin test swore divided in
two groups of TBS<12.9 mg/dl and TBS>12.9 mg/dl. The collected data and demographic
characteristics of the cases were analyzed by SPSS-16 using t and Chi-square tests.
Results: The results show that the average cord blood serum bilirubin was 2.556±0.678
mg/dl and the average for 3rd day after birth was 12.125±2.234 in all the cases. Out of 76
neonates with UCSB<2 mg/dl, 69 neonates had TBS<12.9 mg/dl, 3 days after birth and 7
cases had TBS≥12.9 mg/dl. Out of 261 neonates with UCSB≥2 mg/dl, 150 neonates had
TBS<12.9 mg/dl, 3 days after birth and 111 cases had TBS≥12.9 mg/dl. There was a
significant relationship between umbilical cord serum bilirubin and 3 days after birth
bilirubin score (P<0.001).
Conclusion: Based on the results of this study, it seems that umbilical cord serum
bilirubin can be a predictive value for after birth hyperbilirubinemia in newborns.

Keywords

Hyperbilirubinemia – Infant – Unbilical Cord

© 2013, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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