Clinical and preclinical manifestation of systemic lupus erythmatous

AUTHORS

Mahboubeh Ebrahimpur Fini 1 , Seyedeh Tahereh Faezi 2 , * , Mahmoud Akbarian 3 , Mahsoumeh Akhlaghi 3 , Masoumeh Kheirandish 1 , Ashraf Shahali 1 , Farhad Gharibdoust 3 , Farhad Shahram 3 , Abdolhadi Naji 3 , Ahmadreza Jamshidi 3 , Fereydoun Davachi 3

1 Resident Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran.

2 Assistant Professor Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran.

3 Professor Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran.

How to Cite: Ebrahimpur Fini M, Faezi S T, Akbarian M, Akhlaghi M, Kheirandish M , et al. Clinical and preclinical manifestation of systemic lupus erythmatous, Hormozgan Med J. 2011 ; 15(1):e88379.

ARTICLE INFORMATION

Hormozgan Medical Journal: 15 (1); e88379
Published Online: June 28, 2010
Article Type: Research Article
Received: October 31, 2009
Accepted: June 28, 2010

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Abstract

Introduction: Systemic lupus erythmatous (SLE) is a disease of unknown etiology with
wide variety of clinical and immunological features. Our objective was to describe the
clinical manifestation and laboratory data in Iranian male patients.
Methods: 2279 patients were entered in a cross sectional study. The data were collected
from rheumatologic research center in Shariati hospital of Tehran University. The
prevalence of clinical and immunological features were compared between male and female
patients
Results: 227 patients (9.7%) were male and 2052 (90.3%) patients were female. A higher
frequency of discoid rash and urine casts and a lower frequency of arthritis and leucopenia
were demonstrated in our male patients (P<0.05). The main features were not significantly
alike.
Conclusion: Incidence of coetaneous manifestation and lower incidence of arthritis in men
as well as higher frequency of vital organ involvement such as kidney disease in male
patients should be considered in clinical judgment and treatment planning.

Keywords

Autoimmune Diseases - Lupus Erythematosus Systemic - Nephritis

© 2011, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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