Nasal carrier rates and antibiogram pattern of staphylococcus aureus strains isolated from hospital staff in teaching hospitals in Bandar Abbas

AUTHORS

Afsaneh Karmostaji 1 , Nahid Moradi 1 , Elham Boushehri 2 , * , Marjaneh Jahed 3 , Fariborz Sanginabadi 4 , Banafsheh Dadsetan 4 , Sedigheh Javadpour 5

1 Master of Microbiology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

2 Instructor Department of Biostatistics & Epidemiology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

3 Clinical Lab Technician, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

4 General Practitioner, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

5 Infections Disease Recearch Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

How to Cite: Karmostaji A, Moradi N, Boushehri E, Jahed M, Sanginabadi F, et al. Nasal carrier rates and antibiogram pattern of staphylococcus aureus strains isolated from hospital staff in teaching hospitals in Bandar Abbas, Hormozgan Med J. 2008 ; 12(2):e88942.

ARTICLE INFORMATION

Hormozgan Medical Journal: 12 (2); e88942
Published Online: January 04, 2008
Article Type: Research Article
Received: May 14, 2007
Accepted: January 04, 2008

Crossmark

CHEKING

READ FULL TEXT
Abstract

Introduction:Staphylococcus aureus is one of the most important pathogens in
nosocomial infections. About 30-50% of people harbor this organism in their
nose. Since carrier status in hospital staff is a major source of S. aureus infections
in hospitalized patients, it is of great importance to detect carriers for preventive
strategies.
Methods: In this cross-sectional study, nasal carriage of S. aureus was studied in
200 hospital staff, working in teaching hospitals, in Bandar Abbas. The nasal
swabs of the subjects were cultured on blood agar and manitol salt agar media.
Identification of isolates was performed by catalase, coagulase and DNase tests.
Antibiogram pattern and beta-lactamase activity of isolates were assessed
according to Kirby-Bauer and acidometric methods, respectively.
Results: Nasal carriage state was found in 33 individuals (16%). The maximal
carrier rate was observed in internal ward (40%). The strains were quite resistant
to penicillins and cephalosporins. All of the isolates were sensitive to methicillin
and 94.5% of them were sensitve to imipenem. High degree of sensitivity
(>95%) was also observed to netilin, rifampin and vancomycin. The isolates
were completely resistant to colistin, lincomycin, neomycin and streptomycin.
Penicillinase activity was observed in 27.3% of isolates.
Conclusion: Regarding high frequency of nasal carriage states, more attention
should be paid on screening and treatment of carriers.

Keywords

Staphylococcus aureus - Beta-Lactamase - Carrier - Antibiotic Resistance

© 2008, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

References

  • 1.

    References are included in the PDF.

  • COMMENTS

    LEAVE A COMMENT HERE: