Evaluation of the correlation between fetal well being tests with APGAR score and PH of umbilical artery in high risk pregnant women

AUTHORS

Marziyeh Lotfalizadeh 1 , * , Ashraf Mohammadzadeh 2 , Nayereh Qomian 1 , Elham Kashani 3 , Sakineh Ghorbani 4

1 Assistant Professor, Department of Obstetric & Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Professor, Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Assistant Professor, Department of Obstetric & Gynecology, Gorgan University of Medical Sciences, Gorgan, Iran.

4 Resident, Department of Obstetric & Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.

How to Cite: Lotfalizadeh M, Mohammadzadeh A, Qomian N, Kashani E, Ghorbani S. Evaluation of the correlation between fetal well being tests with APGAR score and PH of umbilical artery in high risk pregnant women, Hormozgan Med J. 2008 ; 12(2):e88950.

ARTICLE INFORMATION

Hormozgan Medical Journal: 12 (2); e88950
Published Online: June 19, 2008
Article Type: Research Article
Received: May 07, 2007
Accepted: June 19, 2008

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Abstract

Introduction: Acidosis-hypoxic phenomenon is a valid indicator to determine
fetal distress and is defined by measuring the blood pH of umblical cord. None of
the present screening tests for evaluation of pregnant mothers have acceptable
clinical accuracy to assess fetal acidosis. We decided to evaluate the relationship
between fetal well being tests Non-Stress Test (NST), Oxytocin Challenge Test
(OCT) and Biophysical Profile (BPP) with APGAR score and the blood pH of
umblical cord.
Methods: In this case-control study, we enrolled 50 high-risk pregnant women (BPP
test positive, OCT positive or non reactive NST) as cases and 50 pregnant women
without fetal risk factors as control group. The umblical cord blood sample was taken
immediately after delivery. Some variables such as maternal age, gestational age,
parity, NST, OCT, BPP, blood pH of umblical cord, neonatal weight, sex and
APGAR score were evaluated and the data was analyzed by SPSS software.
Results: Discrimination between NST with acidosis (P<0.01) was significant in
the case and control groups, but in case of OCT with acidosis it was not
significant. NST and OCT had low sensitivity (58.3 and 46.5 respectively).
Besides, the relationship between BPP and blood pH of umblical cord was
significant in the case and control groups (P<0.02). APGAR score of the cases
were lower than the control group (P<0.0001).
Conclusion: In evaluation of fetal acidosis, the BPP test is the best screening test
comparing to NST and OCT.

Keywords

Non-Stress Test - Contraction Stress Test - Biophysical Profile - APGAR Score - PH - Blood - Umbilical Artery

© 2008, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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