Comparison of the quality of life in patients with chronic obstructive pulmonary disease and control group


Gholamreza KheirAbadi 1 , * , Shahla Akochekian 2 , Siamak Amanat 3 , Mohammad Nemati 4


1 Behavioural Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Department of Psychiatry, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Psychiatrist, Isfahan University of Medical Sciences, Isfahan, Iran.

4 General Practitioner, Isfahan University of Medical Sciences, Isfahan, Iran.


Hormozgan Medical Journal: 12 (4); e89053
Published Online: May 01, 2008
Article Type: Research Article
Received: May 16, 2006
Accepted: May 01, 2008




Introduction: Chronic obstructive pulmonary disease (COPD) is the fourth cause
of mortality and a leading cause of chronic disability worldwide. Given the nature
of the disease and lack of any effective treatment, it can profoundly affect the
quality of life (QOL) of patients. Studies about the effect of COPD on QOL have
yielded contradictory results; however, most studies suggest that COPD
negatively affects QOL. QOL is a concept which is influenced by bio-psychosocial
factors. In this study, we assessed the effect of COPD on QOL of a group
of Iranian patients.
Methods: In this case we assessed QOL in two groups, each consisting of 80
COPD patients as cases and 80 healthy persons control group matched for age,
sex, marital status and education and comparatively similar socioeconomic and
cultural status. The brief WHO-QOL questionnaire was used. Data were analyzed
with SPSS10 using control study, we as t-test. The results were expressed as
means and standard deviations and significance level was set at 0.05.
Results: Analysis of data showed, that mean QOL score and mean scores of the
five aspects of QOL, i.e. disease, independent life, social relations, physical
sensations and mental welfare in the COPD group was significantly lower than in
the control group (P<0/05).
Conclusion: Our findings are indicative of the negative effect of COPD on QOL
in particular. The significantly low levels of QOL in COPD patients demonstrates
that COPD affects not only the patients' physical health but also other aspects of
their lives, leading to decreased QOL. Thus, in spite of ongoing disease,
interventions in these aspects of the patients' lives can improve QOL as a
comprehensive and holistic therapeutic goal.


Chronic Obstructive Pulmonary Disease - Quality of Life

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