Helicobacter pylori serology in pregnant women with hyperemesis gravidarum

AUTHORS

Jhila Abedi Asl 1 , * , Fariba Nateghi 2 , Zahra Etaati 1 , Seyed Alireza Sobhani 3

AUTHORS INFORMATION

1 Assistant Professor Department of Obstetric & Gynecology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

2 Resident of Department of Obstetric & Gynecology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

3 Assistant Professor Department of Pathology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

ARTICLE INFORMATION

Hormozgan Medical Journal: 11 (1); e89061
Published Online: August 26, 2006
Article Type: Research Article
Received: May 25, 2006
Accepted: August 26, 2006

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Abstract

Introduction: Hyperemesis gravidarum (HG) is a relatively common problem.
Despite its obvious effect on quality of life in pregnancy, it can lead to dangerous
complications. This study was conducted to evaluate the hypothesis that there is
meaningful association between hyperemesis gravidarum and gastric infection
with Helicobacter pylori.
Methods: This is a prospective case-control study in which 90 pregnant women aged
15-37 years with gestational age of 6-16 weeks from LMP participated. 40 pregnant
women with hypermesis gravidarum were selected from inpatient pregnants of Dr.
Ali Shariati Hospital as cases and 50 normal pregnant from refereres to obstetric
clinic of hospital as control group randomly. After filling written consent from, 5 cc
venous blood sample was taken for detection of serum IgG and IgM for Helicobacter
pylori and IgG>20 was considered positive. Statistical analysis was performed with
the use of t-test. P-value <0.05 was considered statistically significant.
Results: Seropositivity for Helicobacter pylori was detected in 22 cases out of 40
hyperemetic women (55%) which was not statistically significant. In our study a
significant correlation was seen between high BMI and seropositivity for
Helicobacter pylori in mothers with hyperemesis gravidarum.
Conclusion: Although infection with Helicobacter Pylori in hyperemetic pregnant
women was higher than seronegative ones, it is not statistically significant.

Keywords

Helicobacter Pylori – Hyperemesis Gravidarum - Pregnancy

© 2007, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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