Intra-articular narcotics in pain relieving after arthroscopic meniscectomy of knee: A comparative study

AUTHORS

Hamidreza Arti 1 , Saeid Abrishamkar 2 , Mahmoud Rafieian 3 , *

AUTHORS INFORMATION

1 Assistant professor, Department of Orthopedic, Shahre Kord University of Medical Sciences, Shahr kord, Iran.

2 Assistant professor, Department of Neurosurgery, Shahre Kord University of Medical Sciences, Shahr kord, Iran.

3 Associate Professor, Department of Pharmacology, Shahre Kord University of Medical Sciences, Shahr kord, Iran.

ARTICLE INFORMATION

Hormozgan Medical Journal: 9 (4); e90548
Published Online: March 01, 2006
Article Type: Research Article
Received: July 12, 2005
Accepted: March 01, 2006

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Abstract

Introduction: Knee arthroscopy causes painful signals and if untreated, it will
cause intensive and prolonged pain that may prevent rehabilitation of the patients
for 2 weeks. The analgesic activities of some analgesics, following intra-articular
injection, have been studied before. This study was designed to compare the
analgesic effects of three narcotic analgesics in comparison with the control group.
Methods: In a double blind randomized clinical trial, 110 patients were
designated into four groups. All of them received an intraarticular injection
containing 95 ml bupivacaine with: 1:200000 epinephrine at the end of
arthroscopic procedure in a 10 ml syringe. The remainder of syringe was filled
with one of the following solutions:
Methadone (5mg) for 28 patients, Morphine (5mg) for 23 patients, Normal saline
(5cc) for 28 patients, and Meperidine (50mg) for 27 patients. The patients then
received analgesic based on their needs. The equivalents of analgesics to
morphine were calculated. Other variables including patients need to analgesics
during hospitalization, number of visits from discharge to 7 days later, and pain
scores were also recorded. Data were analyzed by SPSS-12 statistical software
and using Chi-Square and analysis of variance tests.
Results: In morphine group the analgesic usage was significantly low in
hospitalized (P<0.05) and outpatients (P<0.05) compared with the other
groups. There was no complication during the study.
Conclusion: Morphine in comparison with meperidine or methadone is more
beneficial in reducing pain when added to bupivacaine following arthroscopic
meniscectomy.

Keywords

Arthroscopy – Narcotics - Methadone

© 2006, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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