Solitary skull metastasis from follicular thyroid carcinoma: a case report

AUTHORS

Maryam Tohidi 1 , * , Seyed Abdollah Mousavi 1 , Farzad Hadaegh 2

AUTHORS INFORMATION

1 Departments of Pathology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

2 Internal Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

ARTICLE INFORMATION

Hormozgan Medical Journal: 8 (4); e90765
Published Online: December 20, 2004
Article Type: Research Article
Received: August 07, 2004
Accepted: December 20, 2004

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Abstract

Introduction: Follicular thyroid carcinoma (FTC) is the second most common
malignant form of thyroid cancers. FTC is more common in women with a peak
incidence in the fifth and sixth decades of life. Invasion into blood vessels may
lead to distant metastasis to bone, lung, liver or elsewhere.
FTC rarely manifests itself as a distant metastatic lesion, especially as solitary
metastasis.
Case report: Here we present a 65 years old woman with nodular goiter with
cytologic diagnosis of adenomatous goiter.
In follow up, she presented with a skull mass which had an osteolytic appearance
in parietal bone.
Biopsy from skull mass, showed metastasis from FTC. This diagnosis was
confirmed in histologic examination of the thyroidectomy specimen.
Conclusion: Thus, in approaching thyroid nodules, the limitations of fine needle
aspiration-cytology in differentiation of follicular lesions must be remembered.
Also in patients with nodular goiter and evidence of metastasis, possibility of
thyroid carcinomas as primary origin should be considered.

Keywords

Thyroid Neoplasms – Carcinoma – Skull

© 2005, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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