Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes

AUTHORS

Massomeh Yarmohammadi 1 , * , Soleiman Mahjoub 2

1 Department of Exercise Physiology,Islamshahr Branch,Islamic Azad University,Tehran,Iran.

2 Department of Biochemistry,School of Medicine,Babol University of Medical Sciences,Babol,Iran.

How to Cite: Yarmohammadi M , Mahjoub S . Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes, Hormozgan Med J. 2017 ; 21(2):e87284. doi: 10.29252/hmj.21.2.129.

ARTICLE INFORMATION

Hormozgan Medical Journal: 21 (2); e87284
Published Online: August 16, 2017
Article Type: Research Article
Received: March 05, 2017
Accepted: August 16, 2017
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Abstract

Introduction: The aim of this study was to evaluate the effects of aerobic exercise and
pomegranate extract on antioxidant markers in women postmenopausal with type 2
diabetes.
Methods: The statistical population of this study was the postmenopausal diabetic women
of Babol City, North of Iran, who were referred to the Diabetes Association of the city.
Among them, 33 subjects were selected randomly and divided into four groups: Control-
Water (CW), Control-Pomegranate extract (CPE), Training-Water (TW) and Training-
Pomegranate extract (TPE). The experimental group training plan consisted of 6-week
aerobic exercise training, three times a week for at least 45 minutes per session.
Consumer groups of pomegranate extract drank 150 ml of pomegranate extract every day
for 6 weeks. Before and after this interventional study, blood sampling was performed
from the brachial vein in a sitting position in a fasting state. The antioxidant markers of
GPX, SOD, GSH and TAC were measured in the specimens.
Results: The results showed that aerobic exercise training with the consumption of
pomegranate extract significantly increased the levels of glutathione peroxidase and
superoxide dismutase, plasma glutathione and Total Antioxidant Capacity (TAC) in
women with type 2 diabetes compared to the control group (P<0.001). Women with type
2 diabetes in Training-Pomegranate extract groups had the highest levels of the
antioxidants.
Conclusion: Our finding showed that aerobic exercise training associated with the
consumption of pomegranate extract improve the body's antioxidant defense system by
increasing the levels of plasma antioxidants.

Keywords

Aerobic Exercise Pomegranate Extract Antioxidant Type 2 Diabetes

© 2017, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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