Cerebro spinal fluid and serum uric acid in patients with multiple sclerosis

AUTHORS

Mohammad Ali Shafa 1 , Hossein Ali Ebrahimi 2 , * , Fereshteh Esfandiari 3 , Narges Khanjani 4

1 Associate Professor Department of Neuorology, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran.

2 Professor Department of Neurology, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran.

3 Resident of Neurology, Kerman University of Medical Sciences, Kerman, Iran.

4 Associate Professor Department of Epidemiology, Kerman University of Medical Sciences, Kerman, Iran.

How to Cite: Shafa M A, Ebrahimi H A, Esfandiari F, Khanjani N. Cerebro spinal fluid and serum uric acid in patients with multiple sclerosis, Hormozgan Med J. 2014 ; 18(1):e87839.

ARTICLE INFORMATION

Hormozgan Medical Journal: 18 (1); e87839
Published Online: May 27, 2012
Article Type: Research Article
Received: November 20, 2011
Accepted: May 27, 2012

Crossmark

CHEKING

READ FULL TEXT
Abstract

Introduction: Multiple Sclerosis is one of the most common and disabling neurological
disease. Some recent studies showed that the possible role of uric acid in the course of the
disease. The purpose of this study was to evaluate the level of Cerebro Spinal Fluid and
Serum uric acid in patients with multiple sclerosis and compared with control group).
Methods: In this study, Cerebro Spinal Fluid (CSF) and serum uric acid were determined
in 30 patients with MS and compared with 20patients with non inflammatory neurological
disease (NIND), which were matched with age and sex. Data were analyzed with SPSS 17
software and statistical descriptive methods and T-test.
Results: The mean CSF uric acid in patients was 19 mg/dl (SD=0.12) and in the control
group was 0.24 mg/dl (SD=0.19). The mean serum uric acid in patients was 3.95 mg/dl
(SD=1.24) and in the control group was 4.04 mg/dl (SD=1.36). There was no significant
relationship between Cerebro Spinal Fluid (CSF) uric acid in both groups (Pvalue= 0.30),
and also there was no relationship between serum uric acid with both groups
(Pvalue=0.83).
Conclusion: There was no difference in Cerebro Spinal Fluid (CSF) and serum uric acid in
patients with multiple sclerosis and control group.

Keywords

Serum - Multiple Sclerosis - Uric Acid

© 2014, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

References

  • 1.

    References are included in the PDF.

  • COMMENTS

    LEAVE A COMMENT HERE: