Effects of intranasal corticosteroids on decrease of adenoid hypertrophy in children

AUTHORS

Mohammad Bagher Rahmati 1 , Mohammadmehdi Monzavi 2 , Saleh Mohebbi 3 , Mohammd Mehdi Houshmandi 2 , * , Ahmad Malekmohammadi 4 , Yaghoub Hamedi 5

1 Assistant Professor Department of Pediatric, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

2 Pediatrics, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

3 Assisstant Professor Department of Otolaryngologist, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

4 Assisstant Professor Department of Radiology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

5 Associate Professor Department of Parasitology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

How to Cite: Rahmati M B , Monzavi M, Mohebbi S, Houshmandi M M , Malekmohammadi A, et al. Effects of intranasal corticosteroids on decrease of adenoid hypertrophy in children, Hormozgan Med J. 2013 ; 17(5):e88202.

ARTICLE INFORMATION

Hormozgan Medical Journal: 17 (5); e88202
Published Online: December 22, 2012
Article Type: Research Article
Received: August 25, 2012
Accepted: December 22, 2012

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Abstract

Introduction: Adenoid hypertrophy is associated with high morbidity rate in children.
Although surgical treatment is indicated in severe cases, but there are evidences that some
medical interventions are effective in improvement. This study was conducted to evaluate
the effectiveness of corticosteroid nasal spray on reduction of airway obstruction due to
adenoid hypertrophy.
Methods: In a clinical trial study, 50 children aged 2-11 years suffering from excessive
adenoid hypertrophy were administered by Mometason nasal spray in two age groups of 2-4
and 5-11 years for duration of 12-week. All subjects were evaluated for adenoid size and
grade of airway obstruction before and after the intervention by lateral neck radiography.
Results: Radiographic findings and clinical responses were changed significantly after
treatment which was greater in the 2-4 years old group. Adenoid size was significantly less
than its size before treatment and the severity of upper airway obstructive signs and
symptoms decreased in two groups. No side effects reported. Total score of the signs for
nasal obstruction and the rate of airway obstruction by lateral neck radiography were lower
than 12 weeks before drug therapy and the last did not changed during 3 months follow-up.
Conclusion: Topical nasal corticosteroid can lead to decrease in size of the adenoid and the
severity of upper airway obstructive signs and symptoms of children with adenoid
hypertrophy. The effects did not change after 3 months follow-up.

Keywords

Adenoid - Steroids - Obstruction

© 2013, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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