A Comparison survey of the Cognitive function in brief Wechsler intelligence scale between people with and without Beta minor thalassemia

AUTHORS

Fahimeh Yarahmadi 1 , Naser Zangiabadi 2 , * , Ali Darekordi 3 , Mandana Jafari 4

1 General Practitioner, Islamic Azad University, Najaf Abad Unit, Najaf Abad, Iran.

2 Assisstant Professor Department of Neurology, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.

3 PhD of Psychology, Chamran University of Ahvaz, Ahvaz, Iran.

4 MSc Student of Biology, Pharmaceutics Research Center, Kerman University of Medical Sciences, Kerman, Iran.

How to Cite: Yarahmadi F, Zangiabadi N, Darekordi A, Jafari M. A Comparison survey of the Cognitive function in brief Wechsler intelligence scale between people with and without Beta minor thalassemia, Hormozgan Med J. 2014 ; 17(6):e88250.

ARTICLE INFORMATION

Hormozgan Medical Journal: 17 (6); e88250
Published Online: February 06, 2013
Article Type: Research Article
Received: February 13, 2012
Accepted: February 06, 2013

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Abstract

Introduction: The study on effects of various events of physical and Biological-Chemical
abnormality on behavior and cognitive abilities in different areas has always been an
important issue. The aim of this study was to compare the performance of minor betathalassemia
patients with normal people, in the short forms of Wechsler test.
Methods: In This cross-sectional study, a sample including 30 individuals with minor betathalassemia
and 30 normal individuals Whithin age of 18 to 56 years old was selected. The
groups were mathched based on demographic and individual characteristics. Wechsler test
including calculation, words, alignment of images and designing by cubs was performed on
both groups. The results were analysed by SPSS, using t-test and analysis of variance.
Results: The results showed that the average performance of normal individuals for the sub-tests
of computation and words and for sub-test of alignment of images is higher than the performance of
individuals with minor beta-thalassemia. Also in the overall verbal scale (including sub-tests of
calculation and words) the average of performance and ability of the normal individuals was higher
than the individuals with minor beta-thalassemia, while in the overall non-verbal/practical scale
(including sub-tests of alignment of images and designing by cubes) no significant difference was
found between the two groups. The results showed that the average of performance of men and
women in normal individuals and individuals with minor beta-thalassemia in the sub-tests of
calculations and words has a significant difference, while in sub-tests of alignment of images and
designing by cubes for four groups no significant difference between performances was found.
Conclusion: Overall results of this study showed that people with minor beta-thalassemia,
can face lack of abilities such as: fluency in talking, ability of abstract thinking, verbal
reasoning, verbal conceptualization, ability to chain sequences and understanding and
prediction of social situations. Whether such a reduction of abilities is caused by neurological
and neurophysiologic changes or through the psychological effects on individuals with minor
beta-thalassemia, will require further investigation.

Keywords

Beta –Thalassemia - Practical Ability - Verbal Ability

© 2014, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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