Seroepidemiology of Toxoplasma infection of women in child-bearing ages in Chaharmahal va Bakhtiyari province, Iran

AUTHORS

Kourosh Manouchehri Naeini 1 , Seyfollah Mortazaei 2 , * , Soleyman Kheiry 3

1 Associate Professor Department of Parasitologhy, Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

2 MSc of Medical Parasitologhy, Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

3 Associate Professor Department of Biostatistics, Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

How to Cite: Manouchehri Naeini K, Mortazaei S, Kheiry S. Seroepidemiology of Toxoplasma infection of women in child-bearing ages in Chaharmahal va Bakhtiyari province, Iran, Hormozgan Med J. 2014 ; 17(6):e88260.

ARTICLE INFORMATION

Hormozgan Medical Journal: 17 (6); e88260
Published Online: February 11, 2013
Article Type: Research Article
Received: November 30, 2012
Accepted: February 11, 2013

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Abstract

Introduction: Infection of pregnant women with Toxoplasma gondii during pregnancy
may cause congenital toxoplasmosis in embryo and a number of serious and even persistent
complications in newborns. One of the most effective factors determining the rate of
congenital toxoplasmosis is the rate of Toxoplasma infection or immune status of women in
child-bearing ages against the parasite.This study was carried out to investigate the immune
status of women in child-bearing ages (15-45 year-old) against Toxoplasma gondii and
determine the related risk factors in Chaharmahal va Bakhtiyari province.
Methods: This descriptive-analytic study included 338 sera from women in child bearing
ages (15-45 year-old).The sera were examined for the specific anti-Toxoplasma IgG
antibodies using an Enzyme Immunoassay (ELISA) method. Demographic information
were collected through interview and questionnaire forms. The results were analyzed using
SPSS 12 Software and Chi-Square test.
Results: Out of 338 serum samples belonged to the women (mean 25.78±8.21) of the
area, 126 (37.3%) were positive for anti-Toxoplasma IgG antibodies. The highest and
lowest rates of positive reactions were found in 36-45 and 15-25 year-old groups (51.9% vs.
27.9%), respectively (P<0.001). The study also showed a significant correlation between
occupation (P=0.04) and residence (P=0.01) of the subjects with seroreactivity against
Toxoplasma gondii.
Conclusion: The study showed that in this region of the country, a vast majority of women
in child-bearing ages were seronegative for Toxoplama gondii infection (62.7%), and thus
they may be susceptible to acute Toxoplasma infection during their future pregnancy.
Therefore, it is recommended to implement a health education program about transmission
routes of Toxoplasma for the prevention of congenital toxoplasmosis.

Keywords

Toxoplasmosis – Infection - Chaharmahal va Bakhtiari

© 2014, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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