Anti fungal activities of fresh garlic extract on candida albicans

AUTHORS

Mohammad Mehdi Fani 1 , * , Abdolmehdi Araghizadeh 2

1 Assistant Professor Department of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

2 Department of Community Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

How to Cite: Fani M M, Araghizadeh A. Anti fungal activities of fresh garlic extract on candida albicans, Hormozgan Med J. 2009 ; 13(3):e88738.

ARTICLE INFORMATION

Hormozgan Medical Journal: 13 (3); e88738
Published Online: April 28, 2009
Article Type: Research Article
Received: March 05, 2008
Accepted: April 28, 2009

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Abstract

Introduction: Denture stomatitis is one of the most problem in denture wearers and
related to candida albicans. In This study we aimed to determaine garlic extract as an
antifungal agent in oral candidiasis.
Methods: Candida albicans growth in CHROM Agar was made serial dilution from 16 to
512 mg 1-1 from fresh garlic extract and measured minimmum Inhibitory Concentration.
Normal salin was used as control.
Results: Garlic extract showed antifungal activities in 32 mg 1-1 concentration, where
clotrimazol showed its antifungal activity in 64 mg 1-1 concentration and both
Amphoteracin and Nystatin showed their activities in 128 mg 1-1 concentration.
Conclusion: Garlic extract in invitro studies is more than Nystatin, Amphoteracin and
clotrimazol, eventhough, all of the one effective in higher than 128 mg 1-1 concentration.

Keywords

Candida Albicans – Garlic – Antifungal Agents

© 2009, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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