Bacterial isolation and antibiotic resistance of nosocomial pneumonia in hospitalaized patients - Kashan, Iran

AUTHORS

Gholamreza Shajari 1 , * , Ahmad Khorshidi 2 , Seyed Gholamabbas Moosavi 3

1 Associate Professor Department of Microbiology, Kashan University of Medical Sciences, Kashan, Iran.

2 Associate Professor Department of Microbiology, School of Public Health, Kashan University of Medical Sciences, Kashan, Iran.

3 Instructor Department of Statistics, School of Public Health, Kashan University of Medical Sciences, Kashan, Iran.

How to Cite: Shajari G, Khorshidi A, Moosavi S G. Bacterial isolation and antibiotic resistance of nosocomial pneumonia in hospitalaized patients - Kashan, Iran, Hormozgan Med J. 2009 ; 13(3):e88776.

ARTICLE INFORMATION

Hormozgan Medical Journal: 13 (3); e88776
Published Online: April 28, 2009
Article Type: Research Article
Received: April 13, 2008
Accepted: April 28, 2009

Crossmark

CHEKING

READ FULL TEXT
Abstract

Introduction: Bacterial pneumonia occurs in most hospitalized patients where is the
important cause of morbidity and mortality. To reduce the mortality rate, we aimed to
isolate the bacterial agents of pneumonia and determine the antibacterial resistance.
Methods: In this descriptive study, 330 hospitalized patients inffered from bacterial
pneumonia were studied to identify the bacterial agents of pneumoniae and determine
the antibacterial resistant pattern by disk diffusion using Kirby-Bauer method. Medical
records demographic data were gathered by check list. The data were analyzed by
Chi–Square test.
Results: 220 (66.6%) were male and 110 (33.4%) were female. 163 (49.4%) had
underlined disease. The most frequent pathogens were coagulase negative staphylococci
(25%), S. aureus (19.2%), Pseudomonas spp. (19.2%), Klebsiella spp. (17.3%),
Enterobacter spp. (13.5%) and Escherichi coli (5.8%). Coagulase negative staphylococci
were resistant to cloxacillin (80.9%) and cefexim (76.9%). S. aureus was resistant to
cefexim (100%) and oxacillin (81.8%). Pseudomonas spp. were resistant (100%) to
cefazolin and cefexim and highly resistant to other antibiotics. Klebsiella spp,
Enterobacter spp. and Escherichia coli were respectively resistant to the most antibiotics
tested.
Conclusion: This study showed that resistance to antibiotics is increasing. Therefore the
empirical use of antibiotics must be controlled and all isolated bacteria should be tested using
antibacterial susceptibility tests before antibiotic therapy.

Keywords

Pneumonia Bacterial – Antibiotics – Drug Resistance

© 2009, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

References

  • 1.

    References are included in the PDF.

  • COMMENTS

    LEAVE A COMMENT HERE: