Postprandial triglyceride levels in type 2 diabetic patients with and without history of myocardial infarction

AUTHORS

Mohammad Afkhami Ardakani 1 , * , Majid Samsami 2 , Elham Mehravaran 2 , Maryam Rashidi 2

1 Associate Professor Department of Internal Medicine, Yazd University of Medical Sciences, Yazd, Iran.

2 Practitioner, Yazd University of Medical Sciences, Yazd, Iran.

How to Cite: Afkhami Ardakani M, Samsami M, Mehravaran E, Rashidi M. Postprandial triglyceride levels in type 2 diabetic patients with and without history of myocardial infarction, Hormozgan Med J. 2007 ; 11(3):e89534.

ARTICLE INFORMATION

Hormozgan Medical Journal: 11 (3); e89534
Published Online: March 14, 2007
Article Type: Research Article
Received: December 19, 2005
Accepted: March 14, 2007

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Abstract

Introduction: Cardiovascular disease is a major cause of death in diabetic cases.
Studies have shown that hypertriglyceridemia is an important risk factor for
cardiovascular disorders. Although triglyceride level is generally increased in
postprandial periods, the association between postprandial triglyceride level in
diabetic patients and cardiovascular diseases and myocardial infarction (MI) has not
yet been investigated. This study was aimed to determine triglyceride level of type 2
diabetic patients with and without history of MI, before and after meal.
Methods: This clinical trial study consisted of 2 groups of diabetic patients. The first
group included 44 diabetic patients without history of MI. The second ones were 44
diabetic patients that at least 6 months had elapsed since they had MI. Two samples
were collected from all patients: 12 hours after fasting and 2 hours after an ordinary
breakfast (including 315 Kcal). Weight, systolic and diastolic blood pressures of both
hands, waist and hip circumferences, and age were also recorded in the
questionnaire. Data were analyzed by t-test.
Results: mean age of patients was 56.73±10.26 years. Mean weight was
71.67±11.98 kilograms. There was a statistically significant difference between
postprandial (236.73±87.52 mg/dl) and fasting (220.68±91.58 mg/dl) triglyceride
levels in diabetic patients with previous MI (P=0.001), while there was no
significant difference in diabetic patients without previous MI.
Conclusion: This survey revealed that postprandial triglyceride levels in diabetic
patients with previous MI is higher than that in patients without history of MI.
Postprandial hypertriglyceridemia may be an important factor in atherosclerosis
process, hence further investigations is suggested in this concern.

Keywords

Triglycerides – Diabetes Mellitus Type 2 – Myocardial Infarction

© 2007, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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