Radiofrequency catheter ablation in the treatment of Wolff-Parkinson- White syndrome


Mohammad Hassan Namazi 1 , * , Morteza Safi 1 , Roksana Sadeghi 2

1 Department of Cardiology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.

2 Resident of Cardiology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.

How to Cite: Namazi M H, Safi M, Sadeghi R. Radiofrequency catheter ablation in the treatment of Wolff-Parkinson- White syndrome, Hormozgan Med J. 2004 ; 8(1):e90570.


Hormozgan Medical Journal: 8 (1); e90570
Published Online: December 03, 2003
Article Type: Research Article
Received: August 15, 2003
Accepted: December 03, 2003




Introduction: Tachyarrhythmias in Wolf Parkinson White (WPW) syndrome,
can be a life threatening factor. Antiarrhythmic drug therapy in this syndrome,
has not been completely acceptable. Efficacy, safety and economy of Radio
Frequency Catheter Ablation (RFCA) in western studies, has made it as the
treatment of choice. In the present study, efficacy of RFCA in the ablation of
accessory pathway(s) and also, its complication and recurrence rate were studied
in Modarres Hospital, Tehran, Iran.
Methods: In this clinical trial study, 63 patients with WPW syndrome and over
16 years old were selected. Accessory pathway(s) in Electrophysiologic Study
(EPS) laboratory was confirmed and ablation with radiofrequency energy was
performed. If successful, the patients were followed up for one year. The results
were analyzed with Mc Nemar’s method and p<0.05 was considered significant.
Results: Out of sixty three patients, 36 were male and 27 were female with the
mean age of 38.4±14.9 years. The most common accessory pathways were in
left free wall (52.4%) and then in septal region (31.7%), right free wall (9.5%)
and multiple accessory pathways (6.3%). The success rate in the ablation of
accessory pathways, in general, was 90.5%. Maximum success was in septal
pathways (95%) and minimum in right accessory pathways (83%) and in multiple
accessory pathways (75%). There was no meaningful relationship between
efficacy of RFCA and age or sex. There was not any complication. The
recurrence rate in a one year period was 4.8%.
Conclusion: In this study, the result of RFCA in ablation of accessory pathway(s)
and treatment of arrhythmia was comparable with previous western studies. So in
our country, RFCA as the first therapy of choice in WPW syndrome is


Wolff – Parkinson – White Syndrome – Treatment Outcome – Catheter Ablation Radiofrequency

© 2004, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.



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