The prognosis of lupus nephritis in children

AUTHORS

Fatemeh Emamghoreishi 1 , *

1 Department of Pediatrics, Jahrom Faculty of Medical Sciences, Jahrom, Iran.

How to Cite: Emamghoreishi F. The prognosis of lupus nephritis in children, Hormozgan Med J. 2005 ; 8(4):e90729.

ARTICLE INFORMATION

Hormozgan Medical Journal: 8 (4); e90729
Published Online: June 30, 2004
Article Type: Research Article
Received: December 31, 2003
Accepted: June 30, 2004

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Abstract

Introduction: Lupus nephritis is a systemic disease which affects different
organs. The present study was designed to review lupus nephritis, in children its
outcome and the related factors.
Methods: We reviewed 48 children with lupus nephritis. Clinical and
epidemiological features were studied. The patients’ outcomes and related factors
were analyzed. Patient and renal survival rate were calculated.
Results: The patients were aged 3-11 years. All of the patients had proteinuria
and hematuria at the time of presentation. The most common type of renal
pathology was class IV lupus nephritis. In follow up, 29.2% and 25% of patients
had chronic renal failure and hypertension respectively. The most significantly
associated factor was the presence of hypertension at the time of presentation
(p=0.03). Five year renal survival rate was 63.8%.
Conclusion: Age, sex and renal pathology prevalence of children with lupus
nephritis in present study is similar to other studies. Hypertension is a significant
predictive factor, so it needs more attention for early treatment of hypertensive
patient with lupus nephritis. Less favorite renal outcomes in the present study
needs more investigation.

Keywords

Lupus Nephritis – Prognosis – Survival Rate – Child

© 2005, Hormozgan Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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